How New Protein Chips Could Save Your Life Someday

12 | By Michael A. Robinson

Editor’s Note: Michael wrote this article for our sister publication Money Morning on Monday, and it was a big hit with readers. We wanted to make sure you got a chance to see it too. Enjoy.

Ever since some wag came up with the term “Silicon Valley” in the 1970s, investors have thought of semiconductors as the brains behind computers.

Today, semiconductors are about a lot more than computers.

And a few short years from now, those tiny silicon chips that run your PC just may save your life.

See, in a recent breakthrough, a new kind of computer chip was able to spot disease that doctors have a tough time finding on their own.

This new field of cutting-edge high tech could have a big impact on the health of millions around the world. It means we are getting very close to the point when your doctor will be able to detect not just what type of disease you have, but which of many versions is affecting you, too.

What’s more, using these new chips, doctors will have the answer in a matter of minutes. That will speed up everything: the diagnosis, the drugs and – more to the point – your return to good health.

And needless to say, these breakthrough new chips could make a few savvy investors quite rich.

This new field – loosely called “lab on a chip” – holds so much promise that a key research arm of the Pentagon will spend at least $65 million to help get it out of the lab and into the real world.

First let me explain this recent new development.

You may be pleasantly surprised to find out which company is behind it…

The Power of “Protein Chips”

Intel Corp. (NasdaqGS:INTC) has joined forces with a team from Stanford University School of Medicine. The Intel-Stanford team is placing proteins directly on chips to detect disease and help drug firms come up with new compounds.

Just last month, the team said it had synthesized an array of short pieces of proteins on silicon chips normally used as computer microprocessors. Team members said the process will help doctors quickly figure out which of the many possible drugs will work best for each patient.

Proteins are vital to our health. They are large, complex molecules that do most of the work in cells. We need them for the structure, function, and regulation of the body’s tissues and organs.

But it turns out proteins also serve as “markers” for certain diseases…
Take the case of one known as the translocator protein. This substance is highly associated with inflammation of the brain. It’s a signal that the patient could have either multiple sclerosis or Alzheimer’s.

But right now, if they spot translocator protein in your brain, doctors can’t find out quickly which of the two brain diseases you really have. That’s why the Stanford-Intel team wants to use computer chips to help find the exact disease this protein is signaling.

By tapping this tech, they were also able to tell which patients had a very severe form of lupus. That’s a disease in which the immune system turns on itself and attacks the body and can damage organs.

At the very least, team members say, this advance could lead to much better drug trials. In the case of lupus, about half of patients enter these trials with a less severe form of the disease and are less likely to respond to new drugs.

Of course, I believe the Intel-Stanford platform could have a wide impact throughout medicine. Already, the team wants to use the system to design better flu vaccines, which would affect millions in the U.S. alone.

Here’s how Stanford’s Dr. Paul J. Utz described the “protein-on-chip” findings:

“When I see patients in the clinic right now, I may know they have arthritis, but I don’t know which of the 20 or 30 types of the disease they have.

“Now we can measure thousands of protein interactions at a time, integrate this information to diagnose the disease and even determine how severe it may be. We may soon be able to do this routinely while the patient is still in the physician’s office.”

It’s a Virtual Lab on a Chip

That sounds just like what I had in mind when I first alerted my readers about the “lab on chip” field back in late July. At that time, I told you how one of these new devices also could be used to test food safety and warn of biological attacks.

No wonder the Pentagon’s research arm, called DARPA, is investing in this field. In late July, DARPA said it will invest up to $37 million for multiple organ-on-a chip systems designed to mimic the whole human body.

With the funding, a unit of Harvard University wants to build 10 different human organs on a chip. The team intends to link them in a chain to more closely mimic how the human body really works.

Harvard team members see this approach as a more accurate way to predict human responses than to rely on standard animal testing. They also believe the system could speed up the pipeline and U.S. approval of new drugs.

And in a related program, DARPA will provide up to $26.3 million to an MIT lab. This program also focuses on making 10 modules that mimic human systems like those for breathing and moving fluids through the body.

These projects are proof that high tech and science are moving so fast they are turning the world upside down. Every day brings another major advance. I believe that in the near future we will routinely live past 100 and maintain good health along the way.

12 Responses to How New Protein Chips Could Save Your Life Someday

  1. william says:

    The new breakthroughs are good and the ideas for a stronger medical and America is great, but the socialist movement in our country and our medical will destroy, in my opinion the atmosphere for growth, along with stock prices and our economy.

  2. walt pyper says:

    “Potato gnats” that have infested my Irvine, CA, home annually, especially during the month of September 2012, began multiplying rapidly when they found a well-concealed store of potatoes which they quickly “liquefied” to sustain their nesting actvities. As I began to demolish their rapidly growing colony I was targeted by the most mature gnats which entered my nose, ears, eyes, mouth (in short all of the facial organs of my body) that were unprotected from their dive-bombing techniques. Almost immediately I developed a thick mucous in my facial sinuses, and I had to medicate with Robitussin and naproxen sodium (the best I had handy). I assumed that these gnats carried the flu virus that appears at this time of year, but they surprised me when they began a well-orchestrated attack on my face, similar to a bee attack. For lack of a more correct scientific name I now refer to these gnats as “potato gnats” due to their ability to liquify my sack of potatoes which they were strongly attracted to, even though the potatoes were well-hidden next to onions (which they ignored). Does this experience relate in any way to the research you are conducting with micro-chips embedded in the human body. If so, I would like to volunteer as a potential chip recipient.

  3. Steve Kirenz says:

    Thanks for your report on ‘proteins on a chip’ and focus MS and Alzheimer’s
    neuro diseases. I am eager to learn about progress on differentiation of
    proteins already identified for ALS (Lou Gherig’s Disease) causality.

    The DARPA approaches seem to offer more hopeful outcomes than sole
    reliance on the ‘big pharma’ research on multi-trial and error resources
    expended endlessly by the foundations.

  4. Herman Clark says:

    With refference to the comment above, saying that socialized medicine, would destroy ofr slow down the research of the “chip”, is nonsense. The Bush administration stoped or hindered the development of many science project and alot of others, that would have help millions of people. Remember, “I can hear the stemcells crying.” Get your facts straight before politics makes a fool out of you.

  5. Meg Jowett says:

    For someone already diagnosed with Alzheimers or MS, would the protein chip be helpful in improving/refining the medication? Would it also be useful for Parkinsons?

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